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Increased oxidative stress induces high ROS levels and diminishes the interaction between KEAP1 and PGAM5, a mitochondrial serinethreonine phosphatase [74, 160]

This may relate to enzyme activity in wound healing

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doi: 10.1016/j.anai.2022.09.031 123

Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor -dependent mechanism in alzheimer's disease