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diNAC showed greatly reduced antioxidant activity, as treatment with 25 and 50 M diNAC reduced ROS generation by only 20.8% and 12.7% relative to the maximum (Fig

Butyrate acts blocks the IL-6/STAT3/IL-17 and TLR2-MyD88-NF-B pathways, and bidirectionally regulates cytokine secretion, Specifically, it upregulates anti-inflammatory factors such as IL-4 and IL-10 and downregulates pro-inflammatory factors such as CRP, IL-8, IL-12, and TNF- (66, 67, 91, 92)

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