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For the 5-ethynyl-2-deoxyuridine (EdU) assay, approximately 4,000 Huh7 or Hep3B cells were seeded per well in 96-well plates and incubated with 10 M (EdU

Since the liver has an abundant vascular structure and peripheral lymph distribution, ICC is prone to intrahepatic and extrahepatic metastases, and distant metastasis occurs in 70% of clinical autopsies ( Radical surgical resection is currently the only possible curative method for ICC, with a 5-year survival rate of about 30% and a 5-year recurrence rate of 60%70% ( Conclusions ICC with rectal metastasis is a rare mode of distant metastasis that may pose a diagnostic challenge

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Users have reported spontaneous erections and increased sexual desire as side effects, leading to off-label interest in its use for ED

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