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Complementary work using Reactome-derived mitophagy gene sets classified PDAC into low, intermediate, and high mitophagy subtypes, with the high-mitophagy group exhibiting the worst prognosis and a metabolic shift toward glycolysis [126]

The ferroptosis inducer erastin irreversibly inhibits system xc- and synergizes with cisplatin to increase cisplatins cytotoxicity in cancer cells

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115 (10), 26792688 (2005) L.V