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SCFAs have been shown to regulate carbohydrate, lipid and overall energy metabolism, reduce inflammation and adiposity, modulate appetite and promote insulin sensitivity [200, 201] In a study in Indonesia, moderately undernourished children were shown to have lower concentrations of propionate and butyrate [202]

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Zeng L, Liu YP, Sha H, Chen H, Qi L, Smith JA

At follow up visits two years later, their levels of 5MTHF in their CSF had dropped even further