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Multiple systematic review and meta-analyses in the literature on PRP for the treatment of tendinitis and joint pain found that PRP was effective in reducing pain and improving function in many high-quality studies (6-12)

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Possible complications heart failure severe neurological deficits gastric cancer type 1 diabetes rheumatoid arthritis myasthenia gravis (a chronic condition causing muscle weakness) Hashimotos disease (an autoimmune condition affecting the thyroid) A pregnant or nursing person with a B12 deficiency When a person receives treatment for a B12 deficiency, they generally recover well and cease to have symptoms, although they may need to continue to use B12 nutritional supplements