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Heart failure therapy by GLP-1RAs Although a meta-analysis of large-scale clinical trials suggested that GLP-1RAs reduce heart failure hospitalizations (HHF) by approximately 10% in patients with diabetes at high cardiovascular risk [22, 23], the treatment effects on the risk of HHF in individual trials other than AMPLITUDE-O were not significant (Tables 1, 2)

BMC Surgery

But more serious rare risks are also possible, including pancreatitis and stomach or gallbladder problems

GLP-1 agonist drugs, which are synthetic versions of the naturally occurring GLP-1 hormone, have been used for decades in the treatment and management of Type II Diabetes Mellitus (T2DM)

Glucagon-like peptide-1 receptor agonists or GLP-1 RA definition includes a class of medications that act in a similar manner to the GLP-1 hormone