In November 2023, the committee requested additional data from the marketing authorisation holders for Ozempic (semaglutide
It is a GLP-1 receptor agonist, which mimics a naturally occurring peptide hormone that regulates insulin secretion and appetite
When Lilly later announced the Pennsylvania and Alabama projects, they leveraged lessons from Indiana: for retatrutide (a more complex peptide), they hired additional peptide purification experts early and set up parallel pilot campaigns
Diabetes Care (1994) 17(8):9013.10.2337/diacare.17.8.901 55 MeierJJRosenstockJHincelin-MeryARoy-DuvalCDelfolieACoesterHVet alContrasting effects of lixisenatide and liraglutide on postprandial glycemic control, gastric emptying, and safety parameters in patients with type 2 diabetes on optimized insulin glargine with or without metformin: a randomized, open-label trial
And they actually have human data, not just rat studies