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TB-500 appears to influence angiogenesis (new blood vessel growth), cell migration, and tissue repair in animal models

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Products in the 1-3% range typically provide meaningful benefits without overwhelming the skin

GI side effects are most frequent and include nausea (25%44%), diarrhea (19%30%), vomiting (8%24%), constipation (17%24%), and abdominal pain (9%20%) [41, 42, 43, 44, 45, 46]