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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis

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(PubMed) Laird E, O'Halloran AM, Molloy AM, et al

Individuals with diabetes and those suffering from renal diseases experience excessive urinary excretion, leading to high consumption of L-carnitine within the body

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