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And this, I think, of course, there are many ways that you might've been able to extend the half-life, but you were starting with a hormone, a natural hormone neurotransmitter that had such an exquisitely short half-life of basically second or minutes rather than that you could give for a week

Reduced benefits: Using doses that are too low may limit benefit, while stopping or adjusting treatment without follow-up can interfere with long-term metabolic or health goals

doi: 10.1186/s12885-018-4570-8 217 ZhangYXuFLiangHCaiMWenXLiXet al

Nature (1983) 304(5924):36871

The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimers Disease