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Metformin a potentially effective drug for gestational diabetes mellitus: a systematic review and meta-analysis

It causes the ovaries to produce excessive amounts of the male sex hormone androgen due to cysts forming along the outer edges of the organ

Using four sites allows 28 days between injections in the same location, giving tissue adequate time to recover

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Although intentional weight loss may offer modest benefit, most interventions using diet and exercise achieve only small reductions in body weight and show weak effects on oncologic outcomes