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High-affinity interaction of ACE2 and/or NRP1 with the RBD of viral S-protein, followed by cell-mediated furin pre-activation could effectively facilitate host cellular entry of SARS-CoV-2 while evading host immune surveillance 67

Our analytical cohort comprised eleven individuals presenting with 2 patients for single-cell PBMC RNA sequencing and 9 patients for plasma EV proteomics